Cellfie of the Day: Bodo saltans ingesting bacteria, scanning electron micrograp…
Cellfie of the Day: Bodo saltans ingesting bacteria, scanning electron micrograph
Bodo saltans is a free-living kinetoplastic bacterivore related to and predating pathogenic trypanosomes including T. brucei and Leishmania. This image shows a single cell ingesting two bacteria which it catches on the shorter of two flagella and directs to the flagellar pocket for endocytosis. This cell is just over 4 µm long excluding the two flagella.
This image was produced as part of a study aimed at understanding the cellular processes of this organism, in order to provide insight into how it may have evolved to become a devastating human pathogen. Studies have shown that some bacteria, having entered these cells, become activated in order to evade digestion in a way which mimics their behavior inside human macrophages.
Image credit: David Goulding, Wellcome Trust Sanger Institute, Wellcome Images